Title |
Antimicrobial activity of pure platelet-rich plasma against microorganisms isolated from oral cavity
|
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Published in |
BMC Microbiology, February 2013
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DOI | 10.1186/1471-2180-13-47 |
Pubmed ID | |
Authors |
Lorenzo Drago, Monica Bortolin, Christian Vassena, Silvio Taschieri, Massimo Del Fabbro |
Abstract |
Autologous platelet concentrates (PCs) have been extensively used in a variety of medical fields to promote soft and hard tissue regeneration. The significance behind their use lies in the abundance of growth factors in platelets α-granules that promotes wound healing. In addition, antibacterial properties of PCs against various bacteria have been recently pointed out. In this study, the antimicrobial effect of pure platelet-rich plasma (P-PRP) was evaluated against oral cavity microorganisms such as Enterococcus faecalis, Candida albicans, Streptococcus agalactiae, Streptococcus oralis and Pseudomonas aeruginosa. Blood samples were obtained from 17 patients who underwent oral surgery procedures involving the use of P-PRP. The antibacterial activity of P-PRP, evaluated as the minimum inhibitory concentration (MIC), was determined through the microdilution twofold serial method. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 50% |
Nigeria | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 1% |
Chile | 1 | <1% |
Canada | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 149 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 26 | 17% |
Student > Bachelor | 21 | 14% |
Student > Ph. D. Student | 20 | 13% |
Researcher | 19 | 12% |
Student > Postgraduate | 12 | 8% |
Other | 25 | 16% |
Unknown | 32 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 56 | 36% |
Agricultural and Biological Sciences | 18 | 12% |
Biochemistry, Genetics and Molecular Biology | 11 | 7% |
Veterinary Science and Veterinary Medicine | 9 | 6% |
Immunology and Microbiology | 6 | 4% |
Other | 21 | 14% |
Unknown | 34 | 22% |