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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection
|
|---|---|
| Published in |
Retrovirology, February 2013
|
| DOI | 10.1186/1742-4690-10-23 |
| Pubmed ID | |
| Authors |
Caroline Goujon, Torsten Schaller, Rui Pedro Galão, Sarah M Amie, Baek Kim, Kevin Olivieri, Stuart JD Neil, Michael H Malim |
| Abstract |
Type I interferon (IFN) treatment of some cells, including dendritic cells, macrophages and monocytic THP-1 cells, restricts HIV-1 infection and prevents viral cDNA accumulation. Sterile alpha motif and HD domain protein 1 (SAMHD1), a dGTP-regulated deoxynucleotide triphosphohydrolase, reduces HIV-1 infectivity in myeloid cells, likely by limiting dNTPs available for reverse transcription, and has been described as IFNα-inducible. Myeloid cell infection by HIV-1 is enhanced by HIV-2/SIVSM Vpx, which promotes SAMHD1 degradation, or by exogenous deoxyribonucleoside (dN) addition. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| United States | 1 | 1% |
| Denmark | 1 | 1% |
| Unknown | 68 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 25% |
| Researcher | 18 | 25% |
| Student > Bachelor | 7 | 10% |
| Professor > Associate Professor | 7 | 10% |
| Student > Master | 6 | 8% |
| Other | 11 | 15% |
| Unknown | 5 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 38% |
| Immunology and Microbiology | 16 | 22% |
| Biochemistry, Genetics and Molecular Biology | 13 | 18% |
| Medicine and Dentistry | 7 | 10% |
| Veterinary Science and Veterinary Medicine | 1 | 1% |
| Other | 2 | 3% |
| Unknown | 6 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2013.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Retrovirology
#1,213
of 1,273 outputs
Outputs of similar age
#181,602
of 205,493 outputs
Outputs of similar age from Retrovirology
#25
of 26 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,493 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.