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Unraveling the 'TGF-β paradox' one metastamir at a time

Overview of attention for article published in Breast Cancer Research, February 2013
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Title
Unraveling the 'TGF-β paradox' one metastamir at a time
Published in
Breast Cancer Research, February 2013
DOI 10.1186/bcr3383
Pubmed ID
Authors

Danny R Welch, Douglas R Hurst

Abstract

Transforming growth factor beta (TGF-β) has received noteworthy attention in the recent past due to its unique characteristic of functionally switching roles from tumor suppressor to metastasis promoter. To uncover the black box surrounding the mechanisms of TGF-β, Taylor and colleagues performed global miRNA expression analyses using a murine mammary carcinoma progression model. They discovered multiple miRNA regulated by TGF-β and matrix stiffness. Focusing on miR-181a, they uncovered an intricate pathway regulating breast cancer metastasis that sheds new insight into metastasis regulation that may prove useful in clinical settings.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 21%
Researcher 4 21%
Student > Bachelor 2 11%
Student > Master 2 11%
Professor 1 5%
Other 2 11%
Unknown 4 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 32%
Biochemistry, Genetics and Molecular Biology 5 26%
Medicine and Dentistry 3 16%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Immunology and Microbiology 1 5%
Other 1 5%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2013.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Breast Cancer Research
#1,706
of 2,052 outputs
Outputs of similar age
#158,207
of 205,188 outputs
Outputs of similar age from Breast Cancer Research
#25
of 29 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,188 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.