Title |
Over-expression of human cystatin C in pterygium versushealthy conjunctiva
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Published in |
BMC Ophthalmology, February 2013
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DOI | 10.1186/1471-2415-13-6 |
Pubmed ID | |
Authors |
Luis Fernando Barba-Gallardo, Javier Ventura-Juárez, David Kershenobich Stalnikowitz, Rafael Gutiérrez-Campos, Eugenia Torres-Bernal, Luis Fernando Torres-Bernal |
Abstract |
A prospective, non-randomised, transversal and comparative study, carried out in INOVA Vision Institute and Autonomous University of Aguascalientes. Pterygium is an important illness that affects 22% people from tropic and equatorial zones. Is an inflammatory process caused by UV rays, and it has a behavior similar to a neoplasm. For this study was taken into consideration 191 samples from the INOVA Vision Institute, Aguascalientes, Mexico. Include 73 pterygia samples, which were obtained during resection under sterile conditions. 44 normal conjunctiva samples were obtained from the same patients when harvesting the conjunctival autograft, or from other patients undergoing extracapsular cataract extraction from the superior bulbar region. Tears from patients with pterygium (n = 50) and normal volunteers (n = 24) were obtained using a calibrated glass micro capillary tube. The surgical conjunctiva and pterygia samples were subjected to reverse-transcription polymerase chain reaction (RT-PCR), western blot, and immunohistochemistry. Tears were analyzed by enzyme-linked immunosorbent assays. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 4 | 20% |
Other | 3 | 15% |
Student > Postgraduate | 3 | 15% |
Student > Ph. D. Student | 2 | 10% |
Professor | 1 | 5% |
Other | 2 | 10% |
Unknown | 5 | 25% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Environmental Science | 1 | 5% |
Computer Science | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Other | 2 | 10% |
Unknown | 6 | 30% |