Title |
Blomia tropicalis Blo t 5 and Blo t 21 recombinant allergens might confer higher specificity to serodiagnostic assays than whole mite extract
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Published in |
BMC Immunology, February 2013
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DOI | 10.1186/1471-2172-14-11 |
Pubmed ID | |
Authors |
Kellyanne dos Anjos Carvalho, Osvaldo Pompílio de Melo-Neto, Franklin Barbalho Magalhães, João Carlos Marques Ponte, Filipe Adriano Borba Felipe, Mariese Conceição Alves dos Santos, Givaneide dos Santos Lima, Álvaro Augusto Cruz, Carina Silva Pinheiro, Lain Carlos Pontes-de-Carvalho, Neuza Maria Alcantara-Neves |
Abstract |
Blomia tropicalis is a dust mite and an important source of allergens in tropical regions. Up to now, the assays to diagnose atopy to this mite use whole body extract as antigens. However, anti-B. tropicalis IgE antibodies cross-react with Ascaris lumbricoides antigens, hindering the diagnosis of allergy to this mite. In this study, B. tropicalis recombinant allergens were evaluated with the purpose of developing an immunodiagnostic assay for allergy to this mite with greater specificity than those commercially available. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 15% |
Student > Bachelor | 7 | 13% |
Student > Doctoral Student | 6 | 11% |
Student > Master | 5 | 9% |
Student > Ph. D. Student | 3 | 6% |
Other | 11 | 21% |
Unknown | 13 | 25% |
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Immunology and Microbiology | 6 | 11% |
Biochemistry, Genetics and Molecular Biology | 5 | 9% |
Chemistry | 4 | 8% |
Other | 6 | 11% |
Unknown | 13 | 25% |