Title |
Oral mucosal melanoma treated with carbon ion radiotherapy: a case report
|
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Published in |
Journal of Medical Case Reports, October 2016
|
DOI | 10.1186/s13256-016-1071-8 |
Pubmed ID | |
Authors |
Atsushi Musha, Jun-ichi Saitoh, Katsuyuki Shirai, Satoshi Yokoo, Tatsuya Ohno, Takashi Nakano |
Abstract |
Oral mucosal melanoma is a rare disease with a relatively poor prognosis. Carbon ion radiotherapy has been shown to be effective against radiotherapy-resistant tumors owing to its excellent dose concentration and high biological effect. Our patient was a 66-year-old Japanese man with oral mucosal melanoma of his right maxillary gingiva (T4aN0M0). He received carbon ion radiotherapy at 57.6 Gy (relative biological effectiveness) in 16 fractions for 4 weeks. Concomitant chemotherapy (dacarbazine + nimustine + vincristine) was administered at the same time as carbon ion radiotherapy initiation. Two courses of adjuvant chemotherapy were given after carbon ion radiotherapy. Although he experienced grade 2 acute oral mucositis, his symptoms improved within a few weeks of undergoing carbon ion radiotherapy. He was alive at the time of reporting, 35 months after treatment, without any recurrence. Late toxicity has not been observed. Carbon ion radiotherapy for oral mucosal melanoma resulted in a good local effect. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 8 | 24% |
Student > Master | 5 | 15% |
Other | 4 | 12% |
Librarian | 2 | 6% |
Student > Doctoral Student | 1 | 3% |
Other | 5 | 15% |
Unknown | 9 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 41% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Nursing and Health Professions | 3 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Physics and Astronomy | 1 | 3% |
Other | 3 | 9% |
Unknown | 9 | 26% |