Title |
A 12-week multidomain intervention versus active control to reduce risk of Alzheimer’s disease: study protocol for a randomized controlled trial
|
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Published in |
Trials, February 2013
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DOI | 10.1186/1745-6215-14-60 |
Pubmed ID | |
Authors |
Kaarin J Anstey, Alex Bahar-Fuchs, Pushpani Herath, George W Rebok, Nicolas Cherbuin |
Abstract |
Disappointing results from clinical trials of disease-modifying interventions for Alzheimer's dementia (AD), along with reliable identification of modifiable risk factors in mid life from epidemiological studies, have contributed to calls to invest in risk-reduction interventions. It is also well known that AD-related pathological processes begin more than a decade before the development of clinical signs. These observations suggest that lifestyle interventions might be most effective when targeting non-symptomatic adults at risk of AD. To date, however, the few dementia risk-reduction programs available have targeted individual risk factors and/or were restricted to clinical settings. The current study describes the development of an evidence-based, theoretically-driven multidomain intervention to reduce AD risk in adults at risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | <1% |
Netherlands | 1 | <1% |
Canada | 1 | <1% |
Australia | 1 | <1% |
Unknown | 217 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 43 | 19% |
Student > Ph. D. Student | 32 | 14% |
Student > Bachelor | 24 | 11% |
Researcher | 21 | 9% |
Student > Postgraduate | 10 | 5% |
Other | 32 | 14% |
Unknown | 60 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 18% |
Psychology | 37 | 17% |
Nursing and Health Professions | 20 | 9% |
Social Sciences | 15 | 7% |
Sports and Recreations | 8 | 4% |
Other | 35 | 16% |
Unknown | 66 | 30% |