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Superficial spreading cervical squamous cell carcinoma in situ involving the endometrium: a case report and review of the literature

Overview of attention for article published in Journal of Medical Case Reports, May 2022
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Title
Superficial spreading cervical squamous cell carcinoma in situ involving the endometrium: a case report and review of the literature
Published in
Journal of Medical Case Reports, May 2022
DOI 10.1186/s13256-022-03433-4
Pubmed ID
Authors

Javier Martín-Vallejo, Juan B. Laforga, Patricia Molina-Bellido, Pedro A. Clemente-Pérez

Abstract

The spread of cervical squamous cell carcinoma to the inner surface of the uterus with replacement of the endometrium is rare. Continuity of the lesion must be demonstrated to confirm superficial spread and rule out concomitant endometrial cancer. We present the case of a 66-year-old white woman with superficial spreading squamous cell carcinoma of the cervix that involved the endometrium. Her relevant past history included conization of the cervix to treat cervical intraepithelial neoplasia III with positive margins. She subsequently had three negative cervical vaginal cytology results, each with a positive high-risk human papillomavirus test. Transvaginal ultrasound showed occupation of the entire uterine cavity by dense material consistent with pyometra in addition to myometrial thinning due to tension and cervical dilation. The patient presented with greenish vaginal discharge of 3 months' duration. The cervix was not visible during speculum examination. Access for endometrial sampling was not possible, raising suspicion of post-conization cervical stenosis. The patient was treated with laparoscopic hysterectomy with double adnexectomy. Histologic examination showed superficial squamous cell carcinoma invading the cervix to a depth of 2.8 mm; superficial spreading squamous cell carcinoma in situ was also observed in the lower uterine segment and endometrium. The patient was free of symptoms 12 months after surgery. Squamous cell carcinoma of the cervix with superficial spread to the endometrium is not included in the 2020 (fifth edition) World Health Organization Classification of Female Genital Tract Tumors or the 2018 International Federation of Gynecology and Obstetrics cervical cancer staging system. More clinical cases are needed to identify other prognostic factors and inform clinical practice guidelines on the management of this disease.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 19%
Student > Master 2 13%
Unspecified 1 6%
Professor 1 6%
Other 1 6%
Other 2 13%
Unknown 6 38%
Readers by discipline Count As %
Medicine and Dentistry 7 44%
Biochemistry, Genetics and Molecular Biology 1 6%
Unspecified 1 6%
Immunology and Microbiology 1 6%
Agricultural and Biological Sciences 1 6%
Other 0 0%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2022.
All research outputs
#21,038,338
of 25,839,971 outputs
Outputs from Journal of Medical Case Reports
#2,544
of 4,671 outputs
Outputs of similar age
#334,144
of 445,864 outputs
Outputs of similar age from Journal of Medical Case Reports
#53
of 125 outputs
Altmetric has tracked 25,839,971 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,671 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 445,864 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.