Title |
Complete resection of recurrent and initially unresectable dermatofibrosarcoma protuberans downsized by Imatinib
|
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Published in |
World Journal of Surgical Oncology, March 2013
|
DOI | 10.1186/1477-7819-11-59 |
Pubmed ID | |
Authors |
Dennis A Wicherts, Frits van Coevorden, Houke M Klomp, Martine A van Huizum, J Martijn Kerst, Rick LM Haas, Hester H van Boven, JA van der Hage |
Abstract |
Curative surgical treatment of recurrent, locally advanced dermatofibrosarcoma protuberans is often limited owing to a close relation of the tumor with important anatomical structures. Targeted therapy with imatinib, a tyrosine kinase inhibitor, may cause significant reduction of tumor volume, thereby enabling radical surgery. This treatment strategy, therefore, offers a chance of cure for selected patients with advanced dermatofibrosarcoma protuberans. In addition, preoperative treatment with imatinib may decrease possible disfigurement related to radical surgery for large tumors. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 3 | 23% |
Other | 2 | 15% |
Student > Bachelor | 2 | 15% |
Student > Doctoral Student | 1 | 8% |
Student > Ph. D. Student | 1 | 8% |
Other | 1 | 8% |
Unknown | 3 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 38% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
Agricultural and Biological Sciences | 1 | 8% |
Business, Management and Accounting | 1 | 8% |
Psychology | 1 | 8% |
Other | 1 | 8% |
Unknown | 3 | 23% |