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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Adiposity and grip strength: a Mendelian randomisation study in UK Biobank
|
|---|---|
| Published in |
BMC Medicine, June 2022
|
| DOI | 10.1186/s12916-022-02393-2 |
| Pubmed ID | |
| Authors |
Snehal M. Pinto Pereira, Victoria Garfield, Aliki-Eleni Farmaki, David J. Tomlinson, Thomas Norris, Ghazaleh Fatemifar, Spiros Denaxas, Chris Finan, Rachel Cooper |
| Abstract |
Muscle weakness, which increases in prevalence with age, is a major public health concern. Grip strength is commonly used to identify weakness and an improved understanding of its determinants is required. We aimed to investigate if total and central adiposity are causally associated with grip strength. Up to 470,786 UK Biobank participants, aged 38-73 years, with baseline data on four adiposity indicators (body mass index (BMI), body fat percentage (BF%), waist circumference (WC) and waist-hip-ratio (WHR)) and maximum grip strength were included. We examined sex-specific associations between each adiposity indicator and grip strength. We explored whether associations varied by age, by examining age-stratified associations (< 50 years, 50-59 years, 60-64 years,65 years +). Using Mendelian randomisation (MR), we estimated the strength of the adiposity-grip strength associations using genetic instruments for each adiposity trait as our exposure. In males, observed and MR associations were generally consistent: higher BMI and WC were associated with stronger grip; higher BF% and WHR were associated with weaker grip: 1-SD higher BMI was associated with 0.49 kg (95% CI: 0.45 kg, 0.53 kg) stronger grip; 1-SD higher WHR was associated with 0.45 kg (95% CI:0.41 kg, 0.48 kg) weaker grip (covariate adjusted observational analyses). Associations of BMI and WC with grip strength were weaker at older ages: in males aged < 50 years and 65 years + , 1-SD higher BMI was associated with 0.93 kg (95% CI: 0.84 kg, 1.01 kg) and 0.13 kg (95% CI: 0.05 kg, 0.21 kg) stronger grip, respectively. In females, higher BF% was associated with weaker grip and higher WC was associated with stronger grip; other associations were inconsistent. Using different methods to triangulate evidence, our findings suggest causal links between adiposity and grip strength. Specifically, higher BF% (in both sexes) and WHR (males only) were associated with weaker grip strength. |
X Demographics
The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 14 | 41% |
| United States | 2 | 6% |
| Sweden | 1 | 3% |
| Japan | 1 | 3% |
| Luxembourg | 1 | 3% |
| Germany | 1 | 3% |
| Greece | 1 | 3% |
| Unknown | 13 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 20 | 59% |
| Scientists | 10 | 29% |
| Practitioners (doctors, other healthcare professionals) | 3 | 9% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 20 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 15% |
| Student > Bachelor | 2 | 10% |
| Student > Ph. D. Student | 1 | 5% |
| Researcher | 1 | 5% |
| Professor > Associate Professor | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 11 | 55% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 3 | 15% |
| Sports and Recreations | 2 | 10% |
| Biochemistry, Genetics and Molecular Biology | 1 | 5% |
| Psychology | 1 | 5% |
| Medicine and Dentistry | 1 | 5% |
| Other | 0 | 0% |
| Unknown | 12 | 60% |
Attention Score in Context
This research output has an Altmetric Attention Score of 45. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2023.
All research outputs
#901,317
of 24,998,746 outputs
Outputs from BMC Medicine
#635
of 3,910 outputs
Outputs of similar age
#21,276
of 435,727 outputs
Outputs of similar age from BMC Medicine
#13
of 101 outputs
Altmetric has tracked 24,998,746 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,910 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.3. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 435,727 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.