Title |
Phosphate decreases urine calcium and increases calcium balance: A meta-analysis of the osteoporosis acid-ash diet hypothesis
|
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Published in |
Nutrition Journal, September 2009
|
DOI | 10.1186/1475-2891-8-41 |
Pubmed ID | |
Authors |
Tanis R Fenton, Andrew W Lyon, Michael Eliasziw, Suzanne C Tough, David A Hanley |
Abstract |
The acid-ash hypothesis posits that increased excretion of "acidic" ions derived from the diet, such as phosphate, contributes to net acidic ion excretion, urine calcium excretion, demineralization of bone, and osteoporosis. The public is advised by various media to follow an alkaline diet to lower their acidic ion intakes. The objectives of this meta-analysis were to quantify the contribution of phosphate to bone loss in healthy adult subjects; specifically, a) to assess the effect of supplemental dietary phosphate on urine calcium, calcium balance, and markers of bone metabolism; and to assess whether these affects are altered by the b) level of calcium intake, c) the degree of protonation of the phosphate. |
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Canada | 1 | 7% |
Greece | 1 | 7% |
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Demographic breakdown
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Scientists | 2 | 13% |
Mendeley readers
Geographical breakdown
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Slovenia | 1 | <1% |
South Africa | 1 | <1% |
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Student > Bachelor | 31 | 23% |
Researcher | 20 | 15% |
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Other | 16 | 12% |
Professor > Associate Professor | 7 | 5% |
Other | 22 | 16% |
Unknown | 19 | 14% |
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