Title |
The cross-sectional GRAS sample: A comprehensive phenotypical data collection of schizophrenic patients
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Published in |
BMC Psychiatry, November 2010
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DOI | 10.1186/1471-244x-10-91 |
Pubmed ID | |
Authors |
Katja Ribbe, Heidi Friedrichs, Martin Begemann, Sabrina Grube, Sergi Papiol, Anne Kästner, Martin F Gerchen, Verena Ackermann, Asieh Tarami, Annika Treitz, Marlene Flögel, Lothar Adler, Josef B Aldenhoff, Marianne Becker-Emner, Thomas Becker, Adelheid Czernik, Matthias Dose, Here Folkerts, Roland Freese, Rolf Günther, Sabine Herpertz, Dirk Hesse, Gunther Kruse, Heinrich Kunze, Michael Franz, Frank Löhrer, Wolfgang Maier, Andreas Mielke, Rüdiger Müller-Isberner, Cornelia Oestereich, Frank-Gerald Pajonk, Thomas Pollmächer, Udo Schneider, Hans-Joachim Schwarz, Birgit Kröner-Herwig, Ursula Havemann-Reinecke, Jens Frahm, Walter Stühmer, Peter Falkai, Nils Brose, Klaus-Armin Nave, Hannelore Ehrenreich |
Abstract |
Schizophrenia is the collective term for an exclusively clinically diagnosed, heterogeneous group of mental disorders with still obscure biological roots. Based on the assumption that valuable information about relevant genetic and environmental disease mechanisms can be obtained by association studies on patient cohorts of ≥ 1000 patients, if performed on detailed clinical datasets and quantifiable biological readouts, we generated a new schizophrenia data base, the GRAS (Göttingen Research Association for Schizophrenia) data collection. GRAS is the necessary ground to study genetic causes of the schizophrenic phenotype in a 'phenotype-based genetic association study' (PGAS). This approach is different from and complementary to the genome-wide association studies (GWAS) on schizophrenia. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Germany | 1 | 25% |
Switzerland | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 3 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Netherlands | 1 | 1% |
Germany | 1 | 1% |
Switzerland | 1 | 1% |
Unknown | 82 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 20% |
Student > Master | 12 | 14% |
Student > Ph. D. Student | 11 | 13% |
Student > Bachelor | 9 | 10% |
Student > Doctoral Student | 6 | 7% |
Other | 16 | 18% |
Unknown | 16 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 16% |
Agricultural and Biological Sciences | 12 | 14% |
Neuroscience | 10 | 11% |
Psychology | 10 | 11% |
Biochemistry, Genetics and Molecular Biology | 6 | 7% |
Other | 14 | 16% |
Unknown | 21 | 24% |