23c) Other retrospective data not as positive. One review showed #andexanet ⬆️odds of achieving hemostatic efficacy v 4F-PCC* (85.8% vs 68.1%; OR 2.73; 95% CI 1.16-6.42) & odds of mortality (7.9% vs 19.6%; 0.36; 0.13-0.98) * ~80% received 25units/kg 🔓
4,154 followers
10,605 followers
RT @cardiomet_CE: 24) A propensity score analysis in @crit_care found ⬆️odds of achieving hemostasis with #andexanet (85.8% vs 68.1%; OR 2.…
4,154 followers
24) A propensity score analysis in @crit_care found ⬆️odds of achieving hemostasis with #andexanet (85.8% vs 68.1%; OR 2.73; 95% CI 1.16–6.42). The Andexanet cohort was derived from #ANNEXA-4. A synthetic #PCC arm was derived from an observational study. 🔓
4 followers
RT @SCCM_CPP: A two-cohort comparison study by @Olivia_S_Costa et al. included andexanet alfa patients from ANNEXA-4 & a synthetic control…