Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation analyses

RT @MarkQuarter: ..& the combination of 0.195 μM emetine and 6.25 μM remdesivir was observed to achieve 64.9% inhibition of viral yield in…

..& the combination of 0.195 μM emetine and 6.25 μM remdesivir was observed to achieve 64.9% inhibition of viral yield in Vero E6 cells [60]. Therefore, we speculated that emetine might exhibit a powerful therapeutic effect in patients with LUAD/COVID-

"low doses of emetine alone or in combination with ganciclovir have shown satisfactory efficacy in treating human cytomegalovirus, & some recent studies found that emetine may suppress replication of SARS-CoV-2 through targeting PLpro or Mpro, & th

"Molecular docking and MD simulation analyses showed that emetine exhibited excellent binding capacities to DDP4 and the main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)" https://t.co/6XP1ZXMDxU