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Mining for class-specific motifs in protein sequence classification

Overview of attention for article published in BMC Bioinformatics, March 2013
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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6 X users

Citations

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22 Dimensions

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Title
Mining for class-specific motifs in protein sequence classification
Published in
BMC Bioinformatics, March 2013
DOI 10.1186/1471-2105-14-96
Pubmed ID
Authors

Satish M Srinivasan, Suleyman Vural, Brian R King, Chittibabu Guda

Abstract

In protein sequence classification, identification of the sequence motifs or n-grams that can precisely discriminate between classes is a more interesting scientific question than the classification itself. A number of classification methods aim at accurate classification but fail to explain which sequence features indeed contribute to the accuracy. We hypothesize that sequences in lower denominations (n-grams) can be used to explore the sequence landscape and to identify class-specific motifs that discriminate between classes during classification. Discriminative n-grams are short peptide sequences that are highly frequent in one class but are either minimally present or absent in other classes. In this study, we present a new substitution-based scoring function for identifying discriminative n-grams that are highly specific to a class.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Switzerland 1 2%
Brazil 1 2%
Russia 1 2%
United States 1 2%
Unknown 50 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 33%
Student > Master 9 16%
Researcher 5 9%
Student > Bachelor 5 9%
Lecturer 4 7%
Other 6 11%
Unknown 8 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 27%
Computer Science 14 25%
Biochemistry, Genetics and Molecular Biology 6 11%
Neuroscience 3 5%
Chemistry 2 4%
Other 5 9%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2013.
All research outputs
#6,922,951
of 22,701,287 outputs
Outputs from BMC Bioinformatics
#2,683
of 7,254 outputs
Outputs of similar age
#58,797
of 196,095 outputs
Outputs of similar age from BMC Bioinformatics
#56
of 146 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 7,254 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,095 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 146 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.