Title |
Difficult to control atopic dermatitis
|
---|---|
Published in |
World Allergy Organization Journal, March 2013
|
DOI | 10.1186/1939-4551-6-6 |
Pubmed ID | |
Authors |
Ulf Darsow, Andreas Wollenberg, Dagmar Simon, Alain Taïeb, Thomas Werfel, Arnold Oranje, Carlo Gelmetti, Ake Svensson, Mette Deleuran, Anne-Marie Calza, Francesca Giusti, Jann Lübbe, Stefania Seidenari, Johannes Ring |
Abstract |
Difficult to control atopic dermatitis (AD) presents a therapeutic challenge and often requires combinations of topical and systemic treatment. Anti-inflammatory treatment of severe AD most commonly includes topical glucocorticosteroids and topical calcineurin antagonists used for exacerbation management and more recently for proactive therapy in selected cases. Topical corticosteroids remain the mainstay of therapy, the topical calcineurin inhibitors tacrolimus and pimecrolimus are preferred in certain locations. Systemic anti-inflammatory treatment is an option for severe refractory cases. Microbial colonization and superinfection contribute to disease exacerbation and thus justify additional antimicrobial / antiseptic treatment. Systemic antihistamines (H1) may relieve pruritus but do not have sufficient effect on eczema. Adjuvant therapy includes UV irradiation preferably of UVA1 wavelength. "Eczema school" educational programs have been proven to be helpful. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 14% |
Canada | 2 | 14% |
Central African Republic | 1 | 7% |
Australia | 1 | 7% |
Argentina | 1 | 7% |
Spain | 1 | 7% |
Kuwait | 1 | 7% |
France | 1 | 7% |
Unknown | 4 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 50% |
Practitioners (doctors, other healthcare professionals) | 3 | 21% |
Scientists | 3 | 21% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 101 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 8 | 8% |
Student > Master | 7 | 7% |
Other | 6 | 6% |
Professor | 5 | 5% |
Student > Bachelor | 5 | 5% |
Other | 18 | 18% |
Unknown | 52 | 51% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 30% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
Agricultural and Biological Sciences | 3 | 3% |
Immunology and Microbiology | 2 | 2% |
Nursing and Health Professions | 2 | 2% |
Other | 7 | 7% |
Unknown | 54 | 53% |