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The impact of KRAS mutations on VEGF-A production and tumour vascular network

Overview of attention for article published in BMC Cancer, March 2013
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4 X users

Citations

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26 Dimensions

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44 Mendeley
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Title
The impact of KRAS mutations on VEGF-A production and tumour vascular network
Published in
BMC Cancer, March 2013
DOI 10.1186/1471-2407-13-125
Pubmed ID
Authors

Agnès Figueras, Maria Antonia Arbos, Maria Teresa Quiles, Francesc Viñals, Josep Ramón Germà, Gabriel Capellà

Abstract

The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is also different, with an increased anaerobic glycolytic metabolism in cells harbouring codon 12 KRAS mutations compared with cells containing codon 13 mutations. We hypothesized that this distinct metabolic behaviour could be associated with different HIF-1α expression and a distinct angiogenic profile.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 18%
Student > Bachelor 7 16%
Student > Ph. D. Student 6 14%
Professor 4 9%
Student > Master 4 9%
Other 8 18%
Unknown 7 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 39%
Medicine and Dentistry 7 16%
Agricultural and Biological Sciences 7 16%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Nursing and Health Professions 1 2%
Other 2 5%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2022.
All research outputs
#14,762,192
of 24,221,802 outputs
Outputs from BMC Cancer
#3,325
of 8,610 outputs
Outputs of similar age
#123,966
of 219,649 outputs
Outputs of similar age from BMC Cancer
#66
of 112 outputs
Altmetric has tracked 24,221,802 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,610 research outputs from this source. They receive a mean Attention Score of 4.5. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 219,649 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.