↓ Skip to main content

The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents

Overview of attention for article published in Arthritis Research & Therapy, December 2000
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
twitter
5 X users
wikipedia
8 Wikipedia pages

Citations

dimensions_citation
188 Dimensions

Readers on

mendeley
138 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents
Published in
Arthritis Research & Therapy, December 2000
DOI 10.1186/ar146
Pubmed ID
Authors

Luis Alberto García Rodríguez, Sonia Hernández-Díaz

Abstract

Most anti-inflammatory drugs have been associated with an increased risk of serious upper gastrointestinal complications. Epidemiological studies have estimated the magnitude of the risk for specific anti-inflammatory drugs. The risk of upper gastrointestinal tract bleeding or perforation increases around twofold with use of oral steroids or low dose aspirin, and increases around fourfold with use of nonaspirin nonsteroidal anti-inflammatory drugs. Acetaminophen at daily doses of 2000 mg and higher has also been associated with an increased risk. Overall, the risk is dose dependent and is greater with more than one anti-inflammatory drug taken simultaneously. Hence, whenever possible, anti-inflammatory drugs should be given in monotherapy and at the lowest effective dose in order to reduce the risk of serious upper gastrointestinal complications.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
United States 1 <1%
Denmark 1 <1%
Singapore 1 <1%
Unknown 134 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 17%
Student > Master 20 14%
Other 18 13%
Student > Ph. D. Student 12 9%
Student > Bachelor 10 7%
Other 23 17%
Unknown 31 22%
Readers by discipline Count As %
Medicine and Dentistry 53 38%
Pharmacology, Toxicology and Pharmaceutical Science 13 9%
Biochemistry, Genetics and Molecular Biology 6 4%
Agricultural and Biological Sciences 5 4%
Chemistry 5 4%
Other 22 16%
Unknown 34 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2022.
All research outputs
#2,277,680
of 25,461,852 outputs
Outputs from Arthritis Research & Therapy
#413
of 3,388 outputs
Outputs of similar age
#3,244
of 114,908 outputs
Outputs of similar age from Arthritis Research & Therapy
#2
of 9 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,388 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 114,908 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.