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Do post-trauma symptoms mediate the relation between neurobiological stress parameters and conduct problems in girls?

Overview of attention for article published in Child and Adolescent Psychiatry and Mental Health, November 2016
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Title
Do post-trauma symptoms mediate the relation between neurobiological stress parameters and conduct problems in girls?
Published in
Child and Adolescent Psychiatry and Mental Health, November 2016
DOI 10.1186/s13034-016-0129-0
Pubmed ID
Authors

Kimberly A. Babel, Tijs Jambroes, Sanne Oostermeijer, Peter M. van de Ven, Arne Popma, Robert R. J. M. Vermeiren, Theo A. H. Doreleijers, Lucres M. C. Jansen

Abstract

Attenuated activity of stress-regulating systems has consistently been reported in boys with conduct problems. Results in studies of girls are inconsistent, which may result from the high prevalence of comorbid post-trauma symptoms. Therefore, the aim of the present study is to investigate post-trauma symptoms as a potential mediator in the relation between stress-regulation systems functioning and conduct problems in female adolescents. The sample consisted of 78 female adolescents (mean age 15.4; SD 1.1) admitted to a closed treatment institution. The diagnosis of disruptive behaviour disorder (DBD) was assessed by a structured interview-the diagnostic interview schedule for children version IV (DISC-IV). To assess post-trauma symptoms and externalizing behaviour problems, self-report questionnaires, youth self report (YSR) and the trauma symptom checklist for Children (TSCC) were used. The cortisol awakenings response (CAR) measured hypothalamic-pituitary-adrenal (HPA) axis activity, whereas autonomous nervous system (ANS) activity was assessed by heart rate (HR), pre-ejection period (PEP) and respiratory sinus arrhythmia (RSA). Independent t-tests were used to compare girls with and without DBD, while path analyses tested for the mediating role of post- trauma symptoms in the relation between stress regulating systems and externalizing behaviour. Females with DBD (n = 37) reported significantly higher rates of post-trauma symptoms and externalizing behaviour problems than girls without DBD (n = 39). Path analysis found no relation between CAR and externalizing behaviour problems. With regard to ANS activity, positive direct effects on externalizing behaviour problems were present for HR (standardized β = 0.306, p = 0.020) and PEP (standardized β = -0.323, p = 0.031), though not for RSA. Furthermore, no relation-whether direct or indirect-could be determined from post-trauma symptoms. Present findings demonstrate that the neurobiological characteristics of female externalizing behaviour differ from males, since girls showed heightened instead of attenuated ANS activity. While the prevalence of post-trauma symptoms was high in girls with DBD, it did not mediate the relation between stress parameters and externalizing behaviour. Clinical implications and future directions are discussed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 16%
Student > Bachelor 7 11%
Student > Master 6 10%
Student > Doctoral Student 5 8%
Researcher 5 8%
Other 7 11%
Unknown 23 37%
Readers by discipline Count As %
Psychology 24 38%
Social Sciences 5 8%
Medicine and Dentistry 5 8%
Neuroscience 2 3%
Nursing and Health Professions 1 2%
Other 4 6%
Unknown 22 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2016.
All research outputs
#17,823,285
of 22,896,955 outputs
Outputs from Child and Adolescent Psychiatry and Mental Health
#530
of 659 outputs
Outputs of similar age
#222,135
of 311,687 outputs
Outputs of similar age from Child and Adolescent Psychiatry and Mental Health
#8
of 10 outputs
Altmetric has tracked 22,896,955 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 659 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,687 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.