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Target blood pressure in sepsis: between a rock and a hard place

Overview of attention for article published in Critical Care, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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11 X users
patent
3 patents

Citations

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7 Dimensions

Readers on

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35 Mendeley
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Title
Target blood pressure in sepsis: between a rock and a hard place
Published in
Critical Care, March 2013
DOI 10.1186/cc12543
Pubmed ID
Authors

François Beloncle, Nicolas Lerolle, Peter Radermacher, Pierre Asfar

Abstract

The optimal target blood pressure in septic shock is still unknown. Therefore, in a long-term, resuscitated porcine model of fecal peritonitis-induced septic shock, Corrêa and colleagues tested whether different titrations of mean arterial pressure (50 to 60 and 75 to 85 mm Hg) would produce different effects on sepsis-related organ dysfunction. The higher blood pressure window was associated with increased needs for fluid resuscitation and norepinephrine support. However, titrating the lower blood pressure range coincided with an increased incidence of acute kidney injury. In contrast, neither the inflammatory response nor tissue mitochondrial activity showed any difference. This research paper in a clinically relevant model elegantly demonstrates that any standard resuscitation strategy may be a double-edged sword with respect to various therapeutic endpoints. Furthermore, it adds an important piece to the puzzle of the complex pathophysiology of sepsis-related acute kidney injury.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 3%
Brazil 1 3%
Unknown 33 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 17%
Student > Postgraduate 5 14%
Other 4 11%
Student > Bachelor 3 9%
Researcher 3 9%
Other 7 20%
Unknown 7 20%
Readers by discipline Count As %
Medicine and Dentistry 23 66%
Agricultural and Biological Sciences 4 11%
Immunology and Microbiology 1 3%
Nursing and Health Professions 1 3%
Unknown 6 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2023.
All research outputs
#3,753,749
of 25,373,627 outputs
Outputs from Critical Care
#2,848
of 6,554 outputs
Outputs of similar age
#30,773
of 210,385 outputs
Outputs of similar age from Critical Care
#34
of 167 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,385 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.