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Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

Overview of attention for article published in Genome Biology, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
facebook
1 Facebook page

Citations

dimensions_citation
203 Dimensions

Readers on

mendeley
297 Mendeley
citeulike
4 CiteULike
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Title
Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes
Published in
Genome Biology, March 2013
DOI 10.1186/gb-2013-14-3-r25
Pubmed ID
Authors

James P Reddington, Sara M Perricone, Colm E Nestor, Judith Reichmann, Neil A Youngson, Masako Suzuki, Diana Reinhardt, Donncha S Dunican, James G Prendergast, Heidi Mjoseng, Bernard H Ramsahoye, Emma Whitelaw, John M Greally, Ian R Adams, Wendy A Bickmore, Richard R Meehan

Abstract

DNA methylation and the Polycomb repression system are epigenetic mechanisms that play important roles in maintaining transcriptional repression. Recent evidence suggests that DNA methylation can attenuate the binding of Polycomb protein components to chromatin and thus plays a role in determining their genomic targeting. However, whether this role of DNA methylation is important in the context of transcriptional regulation is unclear.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 297 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 2%
United Kingdom 3 1%
Netherlands 1 <1%
Sweden 1 <1%
Germany 1 <1%
Canada 1 <1%
Portugal 1 <1%
Japan 1 <1%
Russia 1 <1%
Other 0 0%
Unknown 282 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 97 33%
Researcher 59 20%
Student > Master 28 9%
Student > Bachelor 20 7%
Professor 14 5%
Other 43 14%
Unknown 36 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 117 39%
Biochemistry, Genetics and Molecular Biology 105 35%
Medicine and Dentistry 13 4%
Neuroscience 5 2%
Computer Science 3 1%
Other 15 5%
Unknown 39 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2014.
All research outputs
#4,582,837
of 25,371,288 outputs
Outputs from Genome Biology
#2,717
of 4,467 outputs
Outputs of similar age
#37,000
of 210,193 outputs
Outputs of similar age from Genome Biology
#32
of 42 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,193 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.