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Differential expression analysis for paired RNA-seq data

Overview of attention for article published in BMC Bioinformatics, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

blogs
1 blog
twitter
14 X users

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
180 Mendeley
citeulike
7 CiteULike
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Title
Differential expression analysis for paired RNA-seq data
Published in
BMC Bioinformatics, March 2013
DOI 10.1186/1471-2105-14-110
Pubmed ID
Authors

Lisa M Chung, John P Ferguson, Wei Zheng, Feng Qian, Vincent Bruno, Ruth R Montgomery, Hongyu Zhao

Abstract

RNA-Seq technology measures the transcript abundance by generating sequence reads and counting their frequencies across different biological conditions. To identify differentially expressed genes between two conditions, it is important to consider the experimental design as well as the distributional property of the data. In many RNA-Seq studies, the expression data are obtained as multiple pairs, e.g., pre- vs. post-treatment samples from the same individual. We seek to incorporate paired structure into analysis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 11 6%
United Kingdom 5 3%
France 4 2%
Germany 2 1%
Sweden 2 1%
Brazil 2 1%
Mexico 2 1%
Denmark 2 1%
Taiwan 1 <1%
Other 2 1%
Unknown 147 82%

Demographic breakdown

Readers by professional status Count As %
Researcher 62 34%
Student > Ph. D. Student 41 23%
Other 11 6%
Student > Master 11 6%
Professor > Associate Professor 10 6%
Other 31 17%
Unknown 14 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 89 49%
Biochemistry, Genetics and Molecular Biology 27 15%
Computer Science 15 8%
Medicine and Dentistry 8 4%
Engineering 5 3%
Other 17 9%
Unknown 19 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2013.
All research outputs
#1,949,828
of 22,703,044 outputs
Outputs from BMC Bioinformatics
#497
of 7,254 outputs
Outputs of similar age
#16,869
of 197,838 outputs
Outputs of similar age from BMC Bioinformatics
#12
of 145 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,254 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,838 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 145 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.