Title |
Systematic review and meta-analysis of randomised trials of perioperative outcomes comparing robot-assisted versus open radical cystectomy
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Published in |
BMC Urology, September 2016
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DOI | 10.1186/s12894-016-0177-z |
Pubmed ID | |
Authors |
Zhiyuan Shen, Zhongquan Sun |
Abstract |
With the introduction of robotic surgery, whether the robot-assisted radical cystectomy (RARC) could reduce the perioperative morbidity compared with Open radical cystectomy (ORC) was unknown. Studies reported RARC were reviewed based on all randomized controlled trials (RCTs), which focused on the efficacy of RARC versus ORC. Of the 201 studies from preliminary screening, four RCTs were included. By pooling these studies, there were significant differences in comparison of operative time (p = 0.007), estimated blood loss (EBL) (p < 0.001) and time to diet (p < 0.001) between the RARC group and ORC groups. There was no significant difference regarding perioperative complications (Clavien 2-5, Clavien 3-5), length of stay (LOS), positive surgical margins (PSM) and lymph node positive. This meta-analysis presented evidence for a benefit of EBL, time to diet, similar perioperative complications and oncological outcomes, but a longer operative time in RARC. It is noted that RARC was considered as a comparable surgical procedure to ORC. |
X Demographics
Geographical breakdown
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Denmark | 1 | 20% |
France | 1 | 20% |
United Kingdom | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 5 | 17% |
Student > Bachelor | 5 | 17% |
Student > Ph. D. Student | 5 | 17% |
Lecturer | 2 | 7% |
Researcher | 2 | 7% |
Other | 6 | 20% |
Unknown | 5 | 17% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 50% |
Business, Management and Accounting | 2 | 7% |
Social Sciences | 2 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 4 | 13% |
Unknown | 5 | 17% |