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Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective

Overview of attention for article published in Arthritis Research & Therapy, December 2012
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  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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Citations

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36 Dimensions

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37 Mendeley
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Title
Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective
Published in
Arthritis Research & Therapy, December 2012
DOI 10.1186/ar4115
Pubmed ID
Authors

Serena Bugatti, Antonio Manzo, Roberto Caporali, Carlomaurizio Montecucco

Abstract

ABSTRACT: The synovial tissue stands at the epicenter of joint pathology in rheumatoid arthritis (RA). As a primary target of the disease, studies on the synovium have provided invaluable insights into the mechanisms involved in disease pathogenesis. Recent work has, however, revealed the importance of a previously unseen anatomic compartment in direct contact with the joint space, namely the subchondral bone marrow. Bone marrow edema (BME) visible on magnetic resonance imaging (MRI) is clinically meaningful in both early and late RA as it associates with future development of bone erosions and poor functional outcomes. Although the histopathologic correlates of MRI-based BME in early RA remain obscure, studies in advanced disease are consistent in describing lymphocytic inflammatory infiltrates within the subchondral marrow cavity of affected joints. In this review, we discuss the nature of bone marrow lesions in patients with RA, analyze their relationship with synovitis, and explore their potential contribution to the pathological processes of the disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 24%
Student > Master 6 16%
Researcher 3 8%
Student > Bachelor 2 5%
Student > Postgraduate 2 5%
Other 6 16%
Unknown 9 24%
Readers by discipline Count As %
Medicine and Dentistry 16 43%
Biochemistry, Genetics and Molecular Biology 4 11%
Agricultural and Biological Sciences 2 5%
Unspecified 1 3%
Nursing and Health Professions 1 3%
Other 4 11%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2013.
All research outputs
#14,598,939
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#2,122
of 3,381 outputs
Outputs of similar age
#166,523
of 288,785 outputs
Outputs of similar age from Arthritis Research & Therapy
#18
of 38 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,785 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.