Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway

@DorissLoh I am NOT a biochemistry whiz kid.... however, I am about to go on a "deep dive" & look at the biochem of light/energy generation in humans. thank you to Dr. Loh (PhD) for her sharp focus

melatonin is driving cellular speed of metabolism? How can we measure this? I asked her via facebook.... she is a melatonin whiz kid. I mean endogenous melatonin, not the supplement. I will puzzle it out a bit. https://t.co/r5n3lMYbDU

https://t.co/lDFGK3ZAQ2 Melatonin treatment ameliorated hyperglycaemia-induced impairment of Leydig cell function with simultaneous stimulation of AMPK/SIRT1 activity and the expression of autophagy-related genes. https://t.co/eKdLK15Acw

Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function — Ameliorated hyperglycaemia-induced impairment.. stimulation of AMPK/SIRT1 & autophagy genes.. promoted mitochondrial biogenesis (PGC-1α/NRF1/mtTFA