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Tryptophan degradation in women with breast cancer: a pilot study

Overview of attention for article published in BMC Research Notes, May 2011
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Title
Tryptophan degradation in women with breast cancer: a pilot study
Published in
BMC Research Notes, May 2011
DOI 10.1186/1756-0500-4-156
Pubmed ID
Authors

Debra E Lyon, Jeanne M Walter, Angela R Starkweather, Christine M Schubert, Nancy L McCain

Abstract

Altered tryptophan metabolism and indoleamine 2,3-dioxygenase activity are linked to cancer development and progression. In addition, these biological factors have been associated with the development and severity of neuropsychiatric syndromes, including major depressive disorder. However, this biological mechanism associated with both poor disease outcomes and adverse neuropsychiatric symptoms has received little attention in women with breast cancer. Therefore, a pilot study was undertaken to compare levels of tryptophan and other proteins involved in tryptophan degradation in women with breast cancer to women without cancer, and secondarily, to examine levels in women with breast caner over the course of chemotherapy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 1%
Unknown 72 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Researcher 12 16%
Student > Master 7 10%
Student > Bachelor 7 10%
Student > Postgraduate 5 7%
Other 12 16%
Unknown 14 19%
Readers by discipline Count As %
Medicine and Dentistry 13 18%
Agricultural and Biological Sciences 10 14%
Biochemistry, Genetics and Molecular Biology 9 12%
Chemistry 5 7%
Psychology 4 5%
Other 17 23%
Unknown 15 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2019.
All research outputs
#20,187,333
of 22,703,044 outputs
Outputs from BMC Research Notes
#3,552
of 4,255 outputs
Outputs of similar age
#104,263
of 112,151 outputs
Outputs of similar age from BMC Research Notes
#36
of 42 outputs
Altmetric has tracked 22,703,044 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,255 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 112,151 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.