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Airway epithelial cells initiate the allergen response through transglutaminase 2 by inducing IL-33 expression and a subsequent Th2 response

Overview of attention for article published in Respiratory Research, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

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6 X users
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1 patent
googleplus
1 Google+ user

Citations

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39 Dimensions

Readers on

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58 Mendeley
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Title
Airway epithelial cells initiate the allergen response through transglutaminase 2 by inducing IL-33 expression and a subsequent Th2 response
Published in
Respiratory Research, March 2013
DOI 10.1186/1465-9921-14-35
Pubmed ID
Authors

Keunhee Oh, Myung Won Seo, Ga Young Lee, Ok-Jin Byoun, Hye-Ryun Kang, Sang-Heon Cho, Dong-Sup Lee

Abstract

Transglutaminase 2 (TG2) is a post-translational protein-modifying enzyme that catalyzes the transamidation reaction, producing crosslinked or polyaminated proteins. Increased TG2 expression and activity have been reported in various inflammatory conditions, such as rheumatoid arthritis, inflammation-associated pulmonary fibrosis, and autoimmune encephalitis. In particular, TG2 from epithelial cells is important during the initial inflammatory response in the lung. In this study, we evaluated the role of TG2 in the pathogenesis of allergic asthma, particularly whether TG2 affects initial activation signaling leading to Th2 differentiation against antigens.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Korea, Republic of 1 2%
India 1 2%
Unknown 54 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Researcher 11 19%
Student > Master 9 16%
Student > Doctoral Student 5 9%
Student > Postgraduate 4 7%
Other 8 14%
Unknown 9 16%
Readers by discipline Count As %
Medicine and Dentistry 16 28%
Agricultural and Biological Sciences 13 22%
Biochemistry, Genetics and Molecular Biology 8 14%
Immunology and Microbiology 8 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 3%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2020.
All research outputs
#5,405,155
of 25,373,627 outputs
Outputs from Respiratory Research
#684
of 3,062 outputs
Outputs of similar age
#43,902
of 208,873 outputs
Outputs of similar age from Respiratory Research
#12
of 38 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,873 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.