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Mendeley readers
Attention Score in Context
| Title |
Dysregulation of autophagy and mitochondrial function in Parkinson’s disease
|
|---|---|
| Published in |
Translational Neurodegeneration, October 2016
|
| DOI | 10.1186/s40035-016-0065-1 |
| Pubmed ID | |
| Authors |
Bao Wang, Neeta Abraham, Guodong Gao, Qian Yang |
| Abstract |
Parkinson's disease (PD) is the second most common neurodegenerative disease. Increasing evidence supports that dysregulation of autophagy and mitochondrial function are closely related with PD pathogenesis. In this review, we briefly summarized autophagy pathway, which consists of macroautophagy, microautophagy and chaperone-mediated autophagy (CMA). Then, we discussed the involvement of mitochondrial dysfunction in PD pathogenesis. We specifically reviewed the recent developments in the relationship among several PD related genes, autophagy and mitochondrial dysfunction, followed by the therapeutic implications of these pathways. In conclusion, we propose that autophagy activity and mitochondrial homeostasis are of high importance in the pathogenesis of PD. Better understanding of these pathways can shed light on the novel therapeutic methods for PD prevention and amelioration. |
Mendeley readers
The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 148 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 22% |
| Researcher | 27 | 18% |
| Student > Master | 18 | 12% |
| Student > Bachelor | 15 | 10% |
| Student > Doctoral Student | 5 | 3% |
| Other | 14 | 9% |
| Unknown | 36 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 32 | 22% |
| Neuroscience | 29 | 20% |
| Agricultural and Biological Sciences | 17 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 7% |
| Medicine and Dentistry | 7 | 5% |
| Other | 11 | 7% |
| Unknown | 42 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2016.
All research outputs
#4,835,823
of 25,373,627 outputs
Outputs from Translational Neurodegeneration
#233
of 384 outputs
Outputs of similar age
#73,527
of 318,616 outputs
Outputs of similar age from Translational Neurodegeneration
#3
of 4 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,616 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.