Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain

Overview of attention for article published in BMC Biology, August 2013

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Mitochondrial aberrations in systemic lupus erythematosus pathogenesis: Insights and therapeutic implications

Article in Rheumatology & Autoimmunity (April 2024)

The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitors

Article in Cancer Cell International (April 2024)

Mitochondrial complex I inhibition triggers NAD+-independent glucose oxidation via successive NADPH formation, “futile” fatty acid cycling, and FADH2 oxidation

Article in GeroScience (January 2024)

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