Title |
Possible role of Escherichia coli in propagation and perpetuation of chronic inflammation in ulcerative colitis
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Published in |
BMC Gastroenterology, April 2013
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DOI | 10.1186/1471-230x-13-61 |
Pubmed ID | |
Authors |
Magdalena Pilarczyk-Zurek, Agnieszka Chmielarczyk, Tomasz Gosiewski, Anna Tomusiak, Pawel Adamski, Malgorzata Zwolinska-Wcislo, Tomasz Mach, Piotr B Heczko, Magdalena Strus |
Abstract |
This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract may play a role in the pathogenesis of UC. Several studies have demonstrated proliferation of E. coli in the gut of UC patients. An increase in the number of E. coli in the inflamed tissue is most probably related to the abundance of iron ions produced by the bacteria. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 20% |
Netherlands | 1 | 20% |
United Kingdom | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 65 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 17% |
Researcher | 9 | 14% |
Student > Bachelor | 8 | 12% |
Student > Master | 7 | 11% |
Other | 4 | 6% |
Other | 10 | 15% |
Unknown | 16 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 28% |
Medicine and Dentistry | 16 | 25% |
Immunology and Microbiology | 4 | 6% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Other | 6 | 9% |
Unknown | 16 | 25% |