Title |
LINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis
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Published in |
BMC Neurology, April 2013
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DOI | 10.1186/1471-2377-13-34 |
Pubmed ID | |
Authors |
Elena García-Martín, Oswaldo Lorenzo-Betancor, Carmen Martínez, Pau Pastor, Julián Benito-León, Jorge Millán-Pascual, Patricia Calleja, María Díaz-Sánchez, Diana Pisa, Laura Turpín-Fenoll, Hortensia Alonso-Navarro, Lucía Ayuso-Peralta, Dolores Torrecillas, Elena Lorenzo, José Francisco Plaza-Nieto, José A G Agúndez, Félix Javier Jiménez-Jiménez |
Abstract |
Some recent experimental data suggest a possible role of LINGO-1 in the pathogenesis of multiple sclerosis (MS). In an attempt to identify genetic biomarkers related to MS susceptibility, we genotyped two common SNPs in the LINGO1 gene which have been associated to other neurological conditions, in patients with MS and in healthy subjects. These SNPs are linked to several SNPs within the LINGO1 gene, especially in individuals of Oriental or Caucasian descent. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 25% |
Switzerland | 1 | 25% |
Egypt | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 7% |
Unknown | 28 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 17% |
Student > Ph. D. Student | 4 | 13% |
Professor > Associate Professor | 3 | 10% |
Unspecified | 3 | 10% |
Other | 2 | 7% |
Other | 5 | 17% |
Unknown | 8 | 27% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 9 | 30% |
Neuroscience | 5 | 17% |
Unspecified | 3 | 10% |
Agricultural and Biological Sciences | 3 | 10% |
Psychology | 1 | 3% |
Other | 3 | 10% |
Unknown | 6 | 20% |