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Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription

Overview of attention for article published in Journal of Nanobiotechnology, April 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#44 of 1,384)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

policy
1 policy source
twitter
17 X users
patent
2 patents
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Readers on

mendeley
224 Mendeley
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Title
Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription
Published in
Journal of Nanobiotechnology, April 2013
DOI 10.1186/1477-3155-11-8
Pubmed ID
Authors

Igor D Vilfan, Yu-Chih Tsai, Tyson A Clark, Jeffrey Wegener, Qing Dai, Chengqi Yi, Tao Pan, Stephen W Turner, Jonas Korlach

Abstract

Zero-mode waveguides (ZMWs) are photonic nanostructures that create highly confined optical observation volumes, thereby allowing single-molecule-resolved biophysical studies at relatively high concentrations of fluorescent molecules. This principle has been successfully applied in single-molecule, real-time (SMRT®) DNA sequencing for the detection of DNA sequences and DNA base modifications. In contrast, RNA sequencing methods cannot provide sequence and RNA base modifications concurrently as they rely on complementary DNA (cDNA) synthesis by reverse transcription followed by sequencing of cDNA. Thus, information on RNA modifications is lost during the process of cDNA synthesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 224 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
United Kingdom 1 <1%
Norway 1 <1%
South Africa 1 <1%
Unknown 219 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 53 24%
Researcher 46 21%
Student > Master 22 10%
Student > Bachelor 14 6%
Professor > Associate Professor 9 4%
Other 26 12%
Unknown 54 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 63 28%
Biochemistry, Genetics and Molecular Biology 57 25%
Chemistry 11 5%
Medicine and Dentistry 9 4%
Immunology and Microbiology 6 3%
Other 20 9%
Unknown 58 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2021.
All research outputs
#1,677,054
of 22,660,862 outputs
Outputs from Journal of Nanobiotechnology
#44
of 1,384 outputs
Outputs of similar age
#14,436
of 199,762 outputs
Outputs of similar age from Journal of Nanobiotechnology
#1
of 6 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,384 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,762 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them