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c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells

Overview of attention for article published in Journal of Neuroinflammation, July 2012
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Citations

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Title
c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells
Published in
Journal of Neuroinflammation, July 2012
DOI 10.1186/1742-2094-9-152
Pubmed ID
Authors

Hsi-Lung Hsieh, Chih-Chung Lin, Hui-Ju Chan, Caleb M Yang, Chuen-Mao Yang

Abstract

Endothelin-1 (ET-1) is elevated and participates in the regulation of several brain inflammatory disorders. The deleterious effects of ET-1 on endothelial cells may aggravate brain inflammation mediated through the upregulation of cyclooxygenase-2 (COX-2) gene expression. However, the signaling mechanisms underlying ET-1-induced COX-2 expression in brain microvascular endothelial cells remain unclear.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 19%
Student > Bachelor 3 14%
Student > Ph. D. Student 2 10%
Researcher 2 10%
Student > Master 2 10%
Other 2 10%
Unknown 6 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 19%
Agricultural and Biological Sciences 3 14%
Medicine and Dentistry 3 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Immunology and Microbiology 1 5%
Other 3 14%
Unknown 6 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2013.
All research outputs
#20,189,002
of 22,705,019 outputs
Outputs from Journal of Neuroinflammation
#2,291
of 2,612 outputs
Outputs of similar age
#147,992
of 164,230 outputs
Outputs of similar age from Journal of Neuroinflammation
#58
of 62 outputs
Altmetric has tracked 22,705,019 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,230 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.