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miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors

Overview of attention for article published in Orphanet Journal of Rare Diseases, April 2013
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Title
miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors
Published in
Orphanet Journal of Rare Diseases, April 2013
DOI 10.1186/1750-1172-8-55
Pubmed ID
Authors

Naoe Harafuji, Peter Schneiderat, Maggie C Walter, Yi-Wen Chen

Abstract

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscle disorder, which is linked to the contraction of the D4Z4 array at chromosome 4q35. Recent studies suggest that this shortening of the D4Z4 array leads to aberrant expression of double homeobox protein 4 (DUX4) and causes FSHD. In addition, misregulation of microRNAs (miRNAs) has been reported in muscular dystrophies including FSHD. In this study, we identified a miRNA that is differentially expressed in FSHD myoblasts and investigated its function.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
France 1 2%
Unknown 39 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Researcher 7 17%
Student > Master 4 10%
Student > Postgraduate 3 7%
Professor 2 5%
Other 6 15%
Unknown 10 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 41%
Biochemistry, Genetics and Molecular Biology 8 20%
Medicine and Dentistry 5 12%
Business, Management and Accounting 1 2%
Unknown 10 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2013.
All research outputs
#15,268,549
of 22,705,019 outputs
Outputs from Orphanet Journal of Rare Diseases
#1,776
of 2,600 outputs
Outputs of similar age
#125,039
of 199,925 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#22
of 34 outputs
Altmetric has tracked 22,705,019 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,600 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,925 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.