MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Daily word art by Kesho and article by Tsuboyama et al. at: https://t.co/Tm3IFAm83F https://t.co/SnDNoUhTrA

RT @GenomeBiology: Tsuboyama, @LuWangLab & co show that methyl CpG binding domain proteins 5 and 6 (MBD5/6) recruit BAP1, allowing it to re…

Tsuboyama, @LuWangLab & co show that methyl CpG binding domain proteins 5 and 6 (MBD5/6) recruit BAP1, allowing it to remove monoubiquitin from H2AK119. Drosophila SBA is an ortholog of MBD5/6, and is part of a functionally conserved protein complex. h

RT @LuWangLab: Very excited to share our new studies on how BAP1 complex is stabilized in cancer cells. Thank you @ACS @NIGMS for your sup…