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Treating cancer cachexia to treat cancer

Overview of attention for article published in Skeletal Muscle, January 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

blogs
1 blog
twitter
3 X users

Citations

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44 Dimensions

Readers on

mendeley
60 Mendeley
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Title
Treating cancer cachexia to treat cancer
Published in
Skeletal Muscle, January 2011
DOI 10.1186/2044-5040-1-2
Pubmed ID
Authors

Se-Jin Lee, David J Glass

Abstract

Skeletal muscle wasting is a major component of cachectic states found in a variety of disease settings, including cancer. As increasing caloric intake often provides little benefit in combating muscle loss in cachectic patients, a major research focus has been to develop strategies stimulating muscle anabolic pathways - in an attempt to fight the catabolic pathways induced during cachexia. Two recent papers have reported the beneficial effects of blocking the myostatin/activin signalling pathway in mouse models of cancer cachexia. We discuss the implications of their findings both with respect to the role that this signalling pathway may play in the aetiology of cachexia and with respect to the prospects for targeting this pathway as a therapeutic strategy in patients with cachexia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Hungary 1 2%
Australia 1 2%
Brazil 1 2%
Unknown 55 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 20%
Researcher 8 13%
Student > Master 8 13%
Student > Doctoral Student 7 12%
Student > Bachelor 6 10%
Other 13 22%
Unknown 6 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 37%
Medicine and Dentistry 15 25%
Biochemistry, Genetics and Molecular Biology 7 12%
Sports and Recreations 2 3%
Nursing and Health Professions 1 2%
Other 3 5%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2017.
All research outputs
#3,608,734
of 25,374,647 outputs
Outputs from Skeletal Muscle
#84
of 388 outputs
Outputs of similar age
#21,717
of 193,904 outputs
Outputs of similar age from Skeletal Muscle
#4
of 8 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 388 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,904 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.