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X Demographics
Mendeley readers
Attention Score in Context
Title |
Mutational hotspots in the TP53gene and, possibly, other tumor suppressors evolve by positive selection
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Published in |
Biology Direct, January 2006
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DOI | 10.1186/1745-6150-1-4 |
Pubmed ID | |
Authors |
Galina V Glazko, Vladimir N Babenko, Eugene V Koonin, Igor B Rogozin |
Abstract |
The mutation spectra of the TP53 gene and other tumor suppressors contain multiple hotspots, i.e., sites of non-random, frequent mutation in tumors and/or the germline. The origin of the hotspots remains unclear, the general view being that they represent highly mutable nucleotide contexts which likely reflect effects of different endogenous and exogenous factors shaping the mutation process in specific tissues. The origin of hotspots is of major importance because it has been suggested that mutable contexts could be used to infer mechanisms of mutagenesis contributing to tumorigenesis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 4% |
Germany | 1 | 4% |
Unknown | 26 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 21% |
Student > Ph. D. Student | 5 | 18% |
Student > Master | 4 | 14% |
Student > Bachelor | 3 | 11% |
Professor > Associate Professor | 3 | 11% |
Other | 2 | 7% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 39% |
Biochemistry, Genetics and Molecular Biology | 7 | 25% |
Chemistry | 2 | 7% |
Medicine and Dentistry | 2 | 7% |
Arts and Humanities | 1 | 4% |
Other | 0 | 0% |
Unknown | 5 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2016.
All research outputs
#3,765,857
of 22,705,019 outputs
Outputs from Biology Direct
#157
of 487 outputs
Outputs of similar age
#16,149
of 154,377 outputs
Outputs of similar age from Biology Direct
#7
of 13 outputs
Altmetric has tracked 22,705,019 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 487 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 154,377 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.