"Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases" Lee S, Lee H [..] Kim JS. Genome Biol 2022-10-12. https://t.co/S4BkJd4Ggh DdCBE-NES & mitoTALEN https://t.co/QS7iobO9HE
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RT @GenomeBiology: Lee, Lee, Kim & co improve the efficiency of mitochondrial DNA editing by fusing base editors to a nuclear export signal…
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Lee, Lee, Kim & co improve the efficiency of mitochondrial DNA editing by fusing base editors to a nuclear export signal to prevent off-target nuclear DNA editing, and including mitochondrial-targeted TALENs that cleave unedited DNA https://t.co/W6sgHj
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Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases | Genome Biology | Full Text https://t.co/NMZWGaD7ha