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Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain

Overview of attention for article published in Virology Journal, April 2013
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2 X users

Citations

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14 Dimensions

Readers on

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49 Mendeley
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1 CiteULike
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Title
Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain
Published in
Virology Journal, April 2013
DOI 10.1186/1743-422x-10-116
Pubmed ID
Authors

Sarah L Fordyce, Karoline Bragstad, Svend Stenvang Pedersen, Thøger G Jensen, Bente Gahrn-Hansen, Rod Daniels, Alan Hay, Marie-Louise Kampmann, Christian AW Bruhn, J Victor Moreno-Mayar, María C Ávila-Arcos, M Thomas P Gilbert, Lars P Nielsen

Abstract

Influenza viruses such as swine-origin influenza A(H1N1) virus (A(H1N1)pdm09) generate genetic diversity due to the high error rate of their RNA polymerase, often resulting in mixed genotype populations (intra-host variants) within a single infection. This variation helps influenza to rapidly respond to selection pressures, such as those imposed by the immunological host response and antiviral therapy. We have applied deep sequencing to characterize influenza intra-host variation in a transmission chain consisting of three cases due to oseltamivir-sensitive viruses, and one derived oseltamivir-resistant case.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 2%
Denmark 1 2%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 22%
Researcher 11 22%
Student > Bachelor 8 16%
Student > Doctoral Student 4 8%
Student > Master 4 8%
Other 7 14%
Unknown 4 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 53%
Biochemistry, Genetics and Molecular Biology 8 16%
Immunology and Microbiology 3 6%
Medicine and Dentistry 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 4 8%
Unknown 5 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2013.
All research outputs
#14,166,906
of 22,705,019 outputs
Outputs from Virology Journal
#1,594
of 3,033 outputs
Outputs of similar age
#113,198
of 198,792 outputs
Outputs of similar age from Virology Journal
#37
of 72 outputs
Altmetric has tracked 22,705,019 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,033 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,792 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.