Title |
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases
|
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Published in |
BMC Bioinformatics, December 2008
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DOI | 10.1186/1471-2105-9-528 |
Pubmed ID | |
Authors |
Wei Yu, Anja Wulf, Tiebin Liu, Muin J Khoury, Marta Gwinn |
Abstract |
Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology. Genetic association studies, such as recent genome-wide association studies (GWAS), have provided a springboard for exploring the contribution of inherited genetic variation and gene/environment interactions in relation to disease. Given the capacity of such studies to produce a plethora of information that may then be described in a number of publications, selecting possible disease susceptibility genes and identifying related modifiable risk factors is a major challenge. A Web-based application for finding evidence of such relationships is key to the development of follow-up studies and evidence for translational research. We developed a Web-based application that selects and prioritizes potential disease-related genes by using a highly curated and updated literature database of genetic association studies. The application, called Gene Prospector, also provides a comprehensive set of links to additional data sources. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 4 | 4% |
Switzerland | 1 | 1% |
Italy | 1 | 1% |
Germany | 1 | 1% |
Belgium | 1 | 1% |
Spain | 1 | 1% |
Greece | 1 | 1% |
United States | 1 | 1% |
Unknown | 85 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 33 | 34% |
Student > Ph. D. Student | 23 | 24% |
Student > Master | 8 | 8% |
Professor | 6 | 6% |
Other | 4 | 4% |
Other | 14 | 15% |
Unknown | 8 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 40 | 42% |
Computer Science | 12 | 13% |
Medicine and Dentistry | 12 | 13% |
Biochemistry, Genetics and Molecular Biology | 10 | 10% |
Engineering | 4 | 4% |
Other | 4 | 4% |
Unknown | 14 | 15% |