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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Caveolin-1 in the regulation of cell metabolism: a cancer perspective
|
|---|---|
| Published in |
Molecular Cancer, November 2016
|
| DOI | 10.1186/s12943-016-0558-7 |
| Pubmed ID | |
| Authors |
Zeribe Chike Nwosu, Matthias Philip Ebert, Steven Dooley, Christoph Meyer |
| Abstract |
Caveolin-1 (CAV1) is an oncogenic membrane protein associated with endocytosis, extracellular matrix organisation, cholesterol distribution, cell migration and signaling. Recent studies reveal that CAV1 is involved in metabolic alterations - a critical strategy adopted by cancer cells to their survival advantage. Consequently, research findings suggest that CAV1, which is altered in several cancer types, influences tumour development or progression by controlling metabolism. Understanding the molecular interplay between CAV1 and metabolism could help uncover druggable metabolic targets or pathways of clinical relevance in cancer therapy. Here we review from a cancer perspective, the findings that CAV1 modulates cell metabolism with a focus on glycolysis, mitochondrial bioenergetics, glutaminolysis, fatty acid metabolism, and autophagy. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 197 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Czechia | 1 | <1% |
| Unknown | 196 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 38 | 19% |
| Student > Bachelor | 27 | 14% |
| Researcher | 21 | 11% |
| Student > Master | 16 | 8% |
| Student > Postgraduate | 10 | 5% |
| Other | 23 | 12% |
| Unknown | 62 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 61 | 31% |
| Agricultural and Biological Sciences | 19 | 10% |
| Medicine and Dentistry | 19 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 5% |
| Neuroscience | 4 | 2% |
| Other | 15 | 8% |
| Unknown | 69 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2021.
All research outputs
#14,281,116
of 22,901,818 outputs
Outputs from Molecular Cancer
#903
of 1,726 outputs
Outputs of similar age
#152,355
of 270,398 outputs
Outputs of similar age from Molecular Cancer
#3
of 11 outputs
Altmetric has tracked 22,901,818 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,726 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,398 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.