Title |
VaccImm: simulating peptide vaccination in cancer therapy
|
---|---|
Published in |
BMC Bioinformatics, April 2013
|
DOI | 10.1186/1471-2105-14-127 |
Pubmed ID | |
Authors |
Joachim von Eichborn, Anna Lena Woelke, Filippo Castiglione, Robert Preissner |
Abstract |
Despite progress in conventional cancer therapies, cancer is still one of the leading causes of death in industrial nations. Therefore, an urgent need of progress in fighting cancer remains. A promising alternative to conventional methods is immune therapy. This relies on the fact that low-immunogenic tumours can be eradicated if an immune response against them is induced. Peptide vaccination is carried out by injecting tumour peptides into a patient to trigger a specific immune response against the tumour in its entirety. However, peptide vaccination is a highly complicated treatment and currently many factors like the optimal number of epitopes are not known precisely. Therefore, it is necessary to evaluate how certain parameters influence the therapy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 3% |
Unknown | 35 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 25% |
Student > Bachelor | 5 | 14% |
Student > Master | 5 | 14% |
Student > Ph. D. Student | 4 | 11% |
Professor > Associate Professor | 4 | 11% |
Other | 6 | 17% |
Unknown | 3 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 19% |
Biochemistry, Genetics and Molecular Biology | 6 | 17% |
Medicine and Dentistry | 6 | 17% |
Computer Science | 3 | 8% |
Engineering | 3 | 8% |
Other | 4 | 11% |
Unknown | 7 | 19% |