Title |
Reductive evolution in Streptococcus agalactiaeand the emergence of a host adapted lineage
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Published in |
BMC Genomics, April 2013
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DOI | 10.1186/1471-2164-14-252 |
Pubmed ID | |
Authors |
Isabelle Rosinski-Chupin, Elisabeth Sauvage, Barbara Mairey, Sophie Mangenot, Laurence Ma, Violette Da Cunha, Christophe Rusniok, Christiane Bouchier, Valérie Barbe, Philippe Glaser |
Abstract |
During host specialization, inactivation of genes whose function is no more required is favored by changes in selective constraints and evolutionary bottlenecks. The Gram positive bacteria Streptococcus agalactiae (also called GBS), responsible for septicemia and meningitis in neonates also emerged during the seventies as a cause of severe epidemics in fish farms. To decipher the genetic basis for the emergence of these highly virulent GBS strains and of their adaptation to fish, we have analyzed the genomic sequence of seven strains isolated from fish and other poikilotherms. |
X Demographics
Geographical breakdown
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United Kingdom | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
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Mexico | 1 | 2% |
United States | 1 | 2% |
Unknown | 62 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 12 | 19% |
Researcher | 11 | 17% |
Student > Bachelor | 7 | 11% |
Professor | 4 | 6% |
Other | 4 | 6% |
Other | 12 | 19% |
Unknown | 14 | 22% |
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Immunology and Microbiology | 5 | 8% |
Veterinary Science and Veterinary Medicine | 3 | 5% |
Other | 10 | 16% |
Unknown | 13 | 20% |