Title |
Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system
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Published in |
Neural Development, January 2010
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DOI | 10.1186/1749-8104-5-2 |
Pubmed ID | |
Authors |
Ryan H Lee, Elizabeth A Mills, Neil Schwartz, Mark R Bell, Katherine E Deeg, Edward S Ruthazer, Nicholas Marsh-Armstrong, Carlos D Aizenman |
Abstract |
Imbalances in the regulation of pro-inflammatory cytokines have been increasingly correlated with a number of severe and prevalent neurodevelopmental disorders, including autism spectrum disorder, schizophrenia and Down syndrome. Although several studies have shown that cytokines have potent effects on neural function, their role in neural development is still poorly understood. In this study, we investigated the link between abnormal cytokine levels and neural development using the Xenopus laevis tadpole visual system, a model frequently used to examine the anatomical and functional development of neural circuits. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 4 | 4% |
Portugal | 1 | <1% |
Australia | 1 | <1% |
Chile | 1 | <1% |
China | 1 | <1% |
Mexico | 1 | <1% |
Unknown | 94 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 25 | 24% |
Researcher | 15 | 15% |
Student > Postgraduate | 10 | 10% |
Professor | 8 | 8% |
Student > Bachelor | 7 | 7% |
Other | 22 | 21% |
Unknown | 16 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 23% |
Medicine and Dentistry | 20 | 19% |
Neuroscience | 17 | 17% |
Psychology | 13 | 13% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Other | 3 | 3% |
Unknown | 22 | 21% |