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Discovering motifs that induce sequencing errors

Overview of attention for article published in BMC Bioinformatics, April 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
11 X users
facebook
2 Facebook pages

Readers on

mendeley
137 Mendeley
citeulike
1 CiteULike
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Title
Discovering motifs that induce sequencing errors
Published in
BMC Bioinformatics, April 2013
DOI 10.1186/1471-2105-14-s5-s1
Pubmed ID
Authors

Manuel Allhoff, Alexander Schönhuth, Marcel Martin, Ivan G Costa, Sven Rahmann, Tobias Marschall

Abstract

Elevated sequencing error rates are the most predominant obstacle in single-nucleotide polymorphism (SNP) detection, which is a major goal in the bulk of current studies using next-generation sequencing (NGS). Beyond routinely handled generic sources of errors, certain base calling errors relate to specific sequence patterns. Statistically principled ways to associate sequence patterns with base calling errors have not been previously described. Extant approaches either incur decisive losses in power, due to relating errors with individual genomic positions rather than motifs, or do not properly distinguish between motif-induced and sequence-unspecific sources of errors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 4%
United Kingdom 4 3%
Italy 2 1%
Germany 2 1%
France 1 <1%
Sweden 1 <1%
Unknown 121 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 45 33%
Student > Ph. D. Student 21 15%
Student > Master 18 13%
Other 10 7%
Professor > Associate Professor 7 5%
Other 19 14%
Unknown 17 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 68 50%
Biochemistry, Genetics and Molecular Biology 18 13%
Computer Science 13 9%
Medicine and Dentistry 4 3%
Mathematics 3 2%
Other 9 7%
Unknown 22 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2014.
All research outputs
#1,911,018
of 24,155,398 outputs
Outputs from BMC Bioinformatics
#433
of 7,507 outputs
Outputs of similar age
#15,794
of 202,743 outputs
Outputs of similar age from BMC Bioinformatics
#10
of 136 outputs
Altmetric has tracked 24,155,398 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,507 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,743 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.