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Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34

Overview of attention for article published in Cell Communication and Signaling, April 2013
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Title
Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34
Published in
Cell Communication and Signaling, April 2013
DOI 10.1186/1478-811x-11-25
Pubmed ID
Authors

Konstantinos Poalas, Emeline M Hatchi, Nelia Cordeiro, Sonia M Dubois, Héloïse M Leclair, Claire Leveau, Catherine Alexia, Julie Gavard, Aimé Vazquez, Nicolas Bidère

Abstract

NF-κB is a master gene regulator involved in plethora of biological processes, including lymphocyte activation and proliferation. Reversible ubiquitinylation of key adaptors is required to convey the optimal activation of NF-κB. However the deubiquitinylases (DUBs), which catalyze the removal of these post-translational modifications and participate to reset the system to basal level following T-Cell receptor (TCR) engagement continue to be elucidated.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 10%
Unknown 18 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 25%
Researcher 4 20%
Professor 3 15%
Student > Doctoral Student 3 15%
Student > Master 2 10%
Other 0 0%
Unknown 3 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 30%
Biochemistry, Genetics and Molecular Biology 5 25%
Medicine and Dentistry 2 10%
Psychology 2 10%
Immunology and Microbiology 1 5%
Other 0 0%
Unknown 4 20%