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Mendeley readers
Attention Score in Context
| Title |
Gene therapy for cardiovascular disease mediated by ultrasound and microbubbles
|
|---|---|
| Published in |
Cardiovascular Ultrasound, April 2013
|
| DOI | 10.1186/1476-7120-11-11 |
| Pubmed ID | |
| Authors |
Zhi-Yi Chen, Yan Lin, Feng Yang, Lan Jiang, Shu ping Ge |
| Abstract |
Gene therapy provides an efficient approach for treatment of cardiovascular disease. To realize the therapeutic effect, both efficient delivery to the target cells and sustained expression of transgenes are required. Ultrasound targeted microbubble destruction (UTMD) technique has become a potential strategy for target-specific gene and drug delivery. When gene-loaded microbubble is injected, the ultrasound-mediated microbubble destruction may spew the transported gene to the targeted cells or organ. Meanwhile, high amplitude oscillations of microbubbles increase the permeability of capillary and cell membrane, facilitating uptake of the released gene into tissue and cell. Therefore, efficiency of gene therapy can be significantly improved. To date, UTMD has been successfully investigated in many diseases, and it has achieved outstanding progress in the last two decades. Herein, we discuss the current status of gene therapy of cardiovascular diseases, and reviewed the progress of the delivery of genes to cardiovascular system by UTMD. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 4% |
| Iran, Islamic Republic of | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 52 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 18% |
| Student > Master | 10 | 18% |
| Student > Ph. D. Student | 8 | 14% |
| Student > Bachelor | 7 | 13% |
| Student > Doctoral Student | 3 | 5% |
| Other | 7 | 13% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 10 | 18% |
| Medicine and Dentistry | 9 | 16% |
| Agricultural and Biological Sciences | 8 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Other | 6 | 11% |
| Unknown | 14 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2023.
All research outputs
#7,767,115
of 24,909,203 outputs
Outputs from Cardiovascular Ultrasound
#75
of 323 outputs
Outputs of similar age
#61,864
of 202,135 outputs
Outputs of similar age from Cardiovascular Ultrasound
#2
of 5 outputs
Altmetric has tracked 24,909,203 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 323 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,135 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.