Title |
Primary angiosarcoma of the breast: a case report
|
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Published in |
Diagnostic Pathology, April 2013
|
DOI | 10.1186/1746-1596-8-66 |
Pubmed ID | |
Authors |
Amal Bennani, Layla Chbani, Meryem Lamchahab, Mouhcine Wahbi, Fatimazzahra Fdili Alaoui, Ikram Badioui, Moulay Abdelilah Melhouf, Affaf Amarti |
Abstract |
Primary angiosarcoma of the breast is extremely rare. Radiologic findings are often non specific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the high rates of local recurrence and early development of metastasis. Surgical removal followed by adjuvant chemotherapy seems improve the prognosis. We report a case of a 33- year-old woman with a highly vascular mass in her right breast which is suggestive of malignancy at radiology. Initial core needle biopsy showed a benign hemangioma. The patient underwent a mastectomy. The tumor histology showed papillary formations and vascular structures lined by atypical cells with hyperchromatic nucleus and eosinophilic cytoplasm with solid areas. The tumor cells expressed CD34 and CD31 but were negative for cytokeratin. The diagnosis of angiosarcoma grade III was made. The patient is now receiving chemotherapy. She is still alive. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 29% |
Other | 3 | 18% |
Student > Postgraduate | 2 | 12% |
Student > Master | 2 | 12% |
Student > Doctoral Student | 1 | 6% |
Other | 2 | 12% |
Unknown | 2 | 12% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 59% |
Business, Management and Accounting | 1 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Computer Science | 1 | 6% |
Agricultural and Biological Sciences | 1 | 6% |
Other | 0 | 0% |
Unknown | 3 | 18% |