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Transcriptional pathways associated with the slow growth phenotype of transformed Anaplasma marginale

Overview of attention for article published in BMC Genomics, April 2013
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Title
Transcriptional pathways associated with the slow growth phenotype of transformed Anaplasma marginale
Published in
BMC Genomics, April 2013
DOI 10.1186/1471-2164-14-272
Pubmed ID
Authors

Sebastián Aguilar Pierlé, Gena Kenitra Hammac, Guy H Palmer, Kelly A Brayton

Abstract

The ability to genetically manipulate bacteria has been fundamentally important for both basic biological discovery and translational research to develop new vaccines and antibiotics. Experimental alteration of the genetic content of prokaryotic pathogens has revealed both expected functional relationships and unexpected phenotypic consequences. Slow growth phenotypes have been reported for multiple transformed bacterial species, including extracellular and intracellular pathogens. Understanding the genes and pathways responsible for the slow growth phenotype provides the opportunity to develop attenuated vaccines as well as bacteriostatic antibiotics. Transformed Anaplasma marginale, a rickettsial pathogen, exhibits slow growth in vitro and in vivo as compared to the parent wild type strain, providing the opportunity to identify the underlying genes and pathways associated with this phenotype.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 3%
Colombia 1 3%
Unknown 32 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 32%
Researcher 6 18%
Student > Doctoral Student 5 15%
Student > Master 5 15%
Student > Bachelor 2 6%
Other 1 3%
Unknown 4 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 44%
Biochemistry, Genetics and Molecular Biology 4 12%
Veterinary Science and Veterinary Medicine 2 6%
Medicine and Dentistry 2 6%
Nursing and Health Professions 1 3%
Other 5 15%
Unknown 5 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2013.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from BMC Genomics
#9,840
of 11,244 outputs
Outputs of similar age
#182,859
of 208,644 outputs
Outputs of similar age from BMC Genomics
#155
of 175 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 175 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.