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Symmetrical acrokeratoderma: a case series in Indian patients

Overview of attention for article published in Orphanet Journal of Rare Diseases, November 2016
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Title
Symmetrical acrokeratoderma: a case series in Indian patients
Published in
Orphanet Journal of Rare Diseases, November 2016
DOI 10.1186/s13023-016-0541-9
Pubmed ID
Authors

Keshavamurthy Vinay, Gitesh U. Sawatkar, Uma N. Saikia, Sunil Dogra

Abstract

Symmetrical acrokeratoderma is a recently described dermatosis in young adult males of Chinese descent. In this report, we describe a series of five cases of symmetrical acrokeratoderma from India. All 5 patients had asymptomatic, brownish-black plaques distributed symmetrically over dorsum of hand and feet with variable involvement of wrist, flexural surface of forearm, elbow, ankles, shin and knee joint. Palms and soles were characteristically spared. Typically whitish maceration of the lesions was seen after immersing in water. The disease showed exacerbation in hot and humid climate with spontaneous resolution in winter. Histopathological examination showed basket weave hyperkeratosis, irregular acanthosis and mild peri-vascular lymphomononuclear infiltrate. Loosening of the stratum corneum was seen in post-immersion biopsy specimens. Acitretin appeared to provide symptomatic improvement in the short term without any long-term effect on the natural disease course. The genetic and environmental factors involved in disease causation needs to be elucidated in future. The study was not registered in a trial registry since it was a retrospective analysis of the clinical records and not an interventional/observational study.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 14%
Student > Master 3 14%
Researcher 2 9%
Other 1 5%
Lecturer > Senior Lecturer 1 5%
Other 3 14%
Unknown 9 41%
Readers by discipline Count As %
Medicine and Dentistry 8 36%
Agricultural and Biological Sciences 1 5%
Nursing and Health Professions 1 5%
Chemistry 1 5%
Engineering 1 5%
Other 0 0%
Unknown 10 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2016.
All research outputs
#20,355,479
of 22,903,988 outputs
Outputs from Orphanet Journal of Rare Diseases
#2,472
of 2,630 outputs
Outputs of similar age
#348,883
of 415,136 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#35
of 36 outputs
Altmetric has tracked 22,903,988 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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